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Our latest scientific articles

  • Frisari, S.; Santo, M.; Hosseini, A.; Manzati, M.; Giugliano, M.; Mallamaci, A. Multidimensional Functional Profiling of Human Neuropathogenic FOXG1 Alleles in Primary Cultures of Murine Pallial Precursors. Int. J. Mol. Sci. 2022, 23, 1343. PDF Zenodo
  • Mele LJ, Palestri P, Selmi L (2020) Modeling Selectivity and Cross-sensitivity in membrane-based potentiometric sensors, Proceedings of the 2020 Joint International EUROSOI Workshop and International Conference on Ultimate Integration on Silicon (EUROSOI-ULIS), Caen (France), PDF Zenodo
  • Mele LJ, Palestri P, Selmi L(2020) General model and equivalent circuit for the chemical noise spectrum associated to surface charge fluctuation in potentiometric sensors, IEEE Sensors Journal (Early Access), PDF Zenodo
  • Conrad M, Jolivet RB (2020) Modelling Neuromodulated Information Flow and Energetic Consumption at Thalamic Relay Synapses, Lecture Notes in Computer Science 12397:649-58. PDF Zenodo
  • George R, Chiappalone M, Giugliano M, Levi T, Vassanelli S, Partzsch J, Mayr C. Plasticity and Adaptation in Neuromorphic Biohybrid Systems. iScience. 2020 Sep 23;23(10):101589. doi: 10.1016/j.isci.2020.101589. eCollection 2020 Oct 23.
    [PMID: 33083749] [PMCID: 7554028] [DOI: 10.1016/j.isci.2020.101589]
    PDF Zenodo
  • Leva F, Palestri P, Selmi L. Modelling of vertical nano-needles as sensing devices for neuronal signal recordings. TechRxiv: Preprint. PDF Zenodo
  • Jolivet RB, Magistretti PJ. Spike–frequency adaptation is modulated by interacting currents in an Hodgkin-Huxley-type model: Role of the Na,K–ATPase. bioRxiv 2020.06.12.148437. PDF Zenodo
  • Levenstein D​​, Alvarez VA​, Amarasingham A​, Azab H, Gerkin RC​​, Hasenstaub A​​, Iyer R​, Jolivet RB, Marzen S​, Monaco JD​​, Prinz AA​, Quraishi S, Santamaria F​​, Shivkumar S, Singh MF​, Stockton DB, Traub R​, Rotstein HG,​ Nadim F,​ Redish AD. On the role of theory and modeling in neuroscience. Arxiv: Preprint. PDF Zenodo
  • Mireille Conrad, Renaud B Jolivet Comparative performance of mutual information and transfer entropy for analyzing the balance of information flow and energy consumption at synapses bioRxiv 2020.06.01.127399; doi: Zenodo



<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>IN-FET project: our second review meeting was very successfully!!! Thank you all, especially our PO and our 4 experts! <a href=“”>@meekeee</a> <a href=“”>@JannisMeents</a> <a href=“”>@ka_sigi</a> <a href=“”>@RenaudJolivet</a> <a href=“”>@claudio_verardo</a> <a href=“”>@federicoleva</a> <a href=“”>@EUeic</a> <a href=“”>@NiccoloCalcini</a> <a href=“”>@PPalestri</a> <a href=“”>@Sissaschool</a> <a href=“”></a></p>&mdash; IN-FET Project (@fet_in) <a href=“”>March 9, 2023</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>Congrats to <a href=“”>@claudio_verardo</a>, key collaborator of our <a href=“”></a> project: best master thesis award, in memory of Vincenzo Tagliasco. <a href=“”></a></p>&mdash; IN-FET Project (@fet_in) <a href=“”>September 23, 2022</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”><a href=“”>@meekeee</a> talks about neuroprosthetics at a local science outreach event, organised at <a href=“”>@UniTrieste</a> <a href=“;ref_src=twsrc%5Etfw”>#infet</a> project <a href=“”>@fet_eu</a> <a href=“”></a></p>&mdash; IN-FET Project (@fet_in) <a href=“”>June 9, 2022</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>Thank you all <a href=“;ref_src=twsrc%5Etfw”>#INFET</a> project partners (<a href=“”></a>) for the fruitful time spent together <a href=“”>@Sissaschool</a> over the past two days, at our consortium meeting <a href=“”>@fet_eu</a> <a href=“”></a></p>&mdash; IN-FET Project (@fet_in) <a href=“”>June 9, 2022</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”># TriesteNext <a href=“”>@Sissaschool</a> <a href=“”></a></p>&mdash; Michele Giugliano (@meekeee) <a href=“”>September 24, 2021</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>Science or science fiction? Talking about <a href=“;ref_src=twsrc%5Etfw”>#AI</a> and microchip in the brain at <a href=“;ref_src=twsrc%5Etfw”>#TriesteNext</a> with our scientists<br>Michele Giugliano <a href=“”>@meekeee</a> <br>Diletta Pozzi Davide Zoccolan Luca Heltai and Chiara Sabelli <a href=“”>@chiara_sabelli</a> <a href=“”></a> <a href=“”></a></p>&mdash; SISSA (@Sissaschool) <a href=“”>September 26, 2021</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>We are enjoining our joint <a href=“;ref_src=twsrc%5Etfw”>#FET</a> meeting with <a href=“”>@fet_in</a> very much, and curious to know more about &quot;Ionic Neuromodulation For <a href=“;ref_src=twsrc%5Etfw”>#Epilepsy</a> Treatment&quot;: today meeting coordinator Michele Giugliano <a href=“”>@Sissaschool</a> is stressing some common points and the differences between the two concepts. <a href=“”></a></p>&mdash; HERMES-FET (@HERMES_FET) <a href=“”>March 30, 2021</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>Today at 11:20, I and Simona Cerrato (<a href=“”>@Sissaschool</a> Medialab) will be guest of radio show RADAR <a href=“”>@Rai</a> <a href=“;ref_src=twsrc%5Etfw”>#fvg</a>. Live here: <a href=“”></a> <br><br>We&#39;ll talk about SISSA&#39;s Student Day of Thursday and of the dialogue between biological and silicon neurons. <a href=“”></a></p>&mdash; Michele Giugliano (@meekeee) <a href=“”>February 23, 2021</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“it” dir=“ltr”>Live fra pochi minuti <a href=“”></a> <a href=“”>@leganerd</a> <a href=“”>@fet_in</a> Parliamo di fantascienza e Neuroscienze!</p>&mdash; Michele Giugliano (@meekeee) <a href=“”>January 20, 2021</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>It has been an excellent workshop!! Thank you, everyone! <a href=“”></a></p>&mdash; Michele Giugliano (@meekeee) <a href=“”>January 14, 2021</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>A new approach to <a href=“;ref_src=twsrc%5Etfw”>#neuromodulation</a>: read about the purpose of the IN-FET project summarised here! <a href=“;ref_src=twsrc%5Etfw”>#epilepsy</a> <a href=“;ref_src=twsrc%5Etfw”>#nanotechnologies</a> <a href=“;ref_src=twsrc%5Etfw”>#nanoelectronics</a> <a href=“”>@meekeee</a> <a href=“”>@JannisMeents</a> <a href=“”>@RenaudJolivet</a> <a href=“”>@Valebio83</a> <a href=“”></a></p>&mdash; IN-FET Project (@fet_in) <a href=“”>December 14, 2020</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>Here you can watch the recorded video of the round table &quot;At the interface of <a href=“;ref_src=twsrc%5Etfw”>#AI</a>, <a href=“;ref_src=twsrc%5Etfw”>#Neuroscience</a> and Policy&quot; at the Marie Curie Alumni Association Virtual Conference - Research &amp; Democracy !!! <a href=“”></a> <a href=“”>@meekeee</a> <a href=“”>@RenaudJolivet</a></p>&mdash; IN-FET Project (@fet_in) <a href=“”>November 25, 2020</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>Read a brief account of our workshop on AI, Neuroscience and Policy down here 👇🏻. We talked about these issues with <a href=“”>@nadia_metoui</a>, <a href=“”>@meekeee</a> and <a href=“”>@r_chavarriaga</a>!<a href=“”>@fet_in</a> <a href=“”></a></p>&mdash; Renaud Jolivet (@RenaudJolivet) <a href=“”>November 13, 2020</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>Just accepted in iScience!<a href=“”>@meekeee</a> <a href=“”></a></p>&mdash; Michela Chiappalone (@BrainBowProject) <a href=“”>September 24, 2020</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>Did you miss our talk at the Science in the city Festival <a href=“;ref_src=twsrc%5Etfw”>#esof2020</a> about <a href=“;ref_src=twsrc%5Etfw”>#Nanotechnologies</a> and <a href=“;ref_src=twsrc%5Etfw”>#nanoelectronics</a> to cure the brain? No worries! Follow this link <a href=“”></a> and watch the video (in italian), then subscribe to our Youtube channel!</p>&mdash; IN-FET Project (@fet_in) <a href=“”>September 10, 2020</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“it” dir=“ltr”>Registratevi numerosi e scoprite le &quot;Nanotecnologie e Nanoelettronica per curare il cervello&quot; <a href=“”>@fet_in</a> <a href=“”></a> <a href=“”>@Eventbrite</a></p>&mdash; Valentina Perrera (@Valebio83) <a href=“”>August 26, 2020</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>A fantastic series of events happening in Trieste! <a href=“”></a> Also In-Fet Project <a href=“”>@fet_in</a> will be on stage on the 2nd September!!!! <a href=“”>@meekeee</a> <a href=“”></a></p>&mdash; Valentina Perrera (@Valebio83) <a href=“”>August 19, 2020</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>Hello everybody! What do you immediately think when you hear the word <a href=“;ref_src=twsrc%5Etfw”>#neuroprosthetics</a>? What futuristic outcome of neuroprosthetics&#39; research do you envisage? What do you think should neuroprosthetics&#39; research focus on nowadays? <a href=“”>@AcademicChatter</a> <a href=“”>@OpenAcademics</a></p>&mdash; IN-FET Project (@fet_in) <a href=“”>August 4, 2020</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>The Webmagazine of The University of Modena and Reggio Emilia dedicated to our FET project an article! Find it here (article in italian) &#39;&#39;Oltre i confini: quattro progetti tra nanoelettronica, nanotecnologie e neuroscienze&#39;&#39;. To read it, follow this link <a href=“”></a></p>&mdash; IN-FET Project (@fet_in) <a href=“”>July 28, 2020</a></blockquote> <script async src=“” charset=“utf-8”></script>

<blockquote class=“twitter-tweet”><p lang=“en” dir=“ltr”>Trieste, <a href=“”>@ESOF_eu</a> Science in The City. The IN-FET project organises a dissemination event open to the public, entitled &quot;Nanotechnologies and Nanoelectronics to Cure the Brain&quot;<a href=“”>@fet_eu</a> <a href=“;ref_src=twsrc%5Etfw”>#fetopen</a> <a href=“;ref_src=twsrc%5Etfw”>#sciencecommunication</a> <a href=“”></a></p>&mdash; IN-FET Project (@fet_in) <a href=“”>July 23, 2020</a></blockquote> <script async src=“” charset=“utf-8”></script>


News and Events

On February 22nd 2024, Michele Giugliano has been invited as a speaker to Neuronics Conference in Valencia (Spain).

On September 11th 2023, Prof. Dr. Luca SELMI organized a joint event (i.e. involving three EIC projects: IN-FET, CROSSBRAIN, and BeFerroSynaptic) at the prestigious ESSDERC 2023 conference in Lisbon (Portugal).

On September 29th 2021, Michele Giugliano has been invited to the weekly podcast (in live streaming) by Sanofi e di Startupitalia.

On September 26th 2021, during Trieste Next, Michele Giugliano participated to a round table on Artificial Intelligence and Neuroprosthetics: science fiction or reality?. The event has been directed to the general public and it was held both in presence and streamed online.

On September 23rd 2021, the Italian newspaper ‘’Corriere della Sera’’ explaining the scope of the project IN-FET. “Corriere” website also published the article.

pdf version

On April 15th 2021, international day of researchers, Michele Giugliano has been very briefly interviewed by the RAI, the Italian TV broadcasting company.

Read here an extended account of the interview and here the longer press release: ansa_april2021.pdf

On February 25th 2021, SISSA organised the “Student Day” in a digital format. Michele Giugliano and his colleagues animated a panel discussing a dialogue between artificial and biological neurons. This discussion panel was aimed at high-school students from participating schools, disseminating the latest discoveries in the fields of neuroscience and machine learning.

Watch it here:

On February 23rd 2021, Simona Cerrato (SISSA Medialab) and Michele GIUGLIANO (SISSA) have been guests of the radio show RADAR from the Italian Rai broadcasting. We announced the forthcoming SISSA's Student Day and the science dialogue between silicon neurons and biological neurons, featured at that event.

Listen to it here:

On January 20th 2021, Michele GIUGLIANO (SISSA) was live, hosted by Alessio Vissani, on the Eureka! weekly science podcast of the italian magazine Lega Nerd.

Watch it here:

Lega Nerd is a well known Italian magazine of “nerd/geek” youngster culture in Italy, established more than 10 years ago. It is based on crowdsourcing and characterised by an informal and friendly style.

leganerd_fb.jpeg whatsapp_image_2021-01-20_at_11.30.38.jpeg

On January 14th 2021, Michele Giugliano (SISSA) and Valentina Perrera (SISSA) organised together with the entire IN-FET consortium a workshop on Scientific Communication and Responsible Research and Innovation.

Watch it again below, in case you missed it!

On November 6th 2020, Michele Giugliano (SISSA) and Renaud Jolivet (UNIGE) (remotely) participated to a workshop on AI, Neuroscience and Policy, organised by members of the Marie Curie Alumni Association.

Have you missed it? Read a summary of the workshop here or watch again the session below!!

On September 2nd 2020, the IN-FET consortium organised a science outreach event at the Science in the city festival, focusing on Nanotechnologies and Nanoelectronics to Cure the Brain. Michele Giugliano (SISSA), Pierpaolo Palestri (IUNET-UNIUD), and Luca Selmi (IUNET-UNIMORE) gave three brief talks chaired and moderated by Valentina Perrera (SISSA).

Check the festival's website to discover the programme or watch again our event below!!

In the June 24th 2020 issue of the Italian Panorama magazine, the IN-FET project was featured, with a brief interview to Michele Giugliano (SISSA) on future novel treatments for Parkinson.

The Webmagazine of the University of Modena and Reggio Emilia gave coverage to the IN-FET project!

On February 13th 2020, Michele Giugliano (SISSA) contributed to the SISSA for Schools programme, participating to the Open Day for School Students.

Watch again the coverage of the event by the Italian National Broadcasting TV (RAI), where Michele Giugliano was very briefly interviewed !!

Click here for our “kick-off” press release launched on February 2020.


Call for Applications: Postdoctoral Researcher position on neuronal network electrophysiology and neuroengineering, at SISSA (Trieste, Italy)

A full-time position is available in the Lab for Neuronal Dynamics of the Neuroscience Area at SISSA (The International School of Advanced Studies) in Trieste (Italy).

The topic is in “Experimental validation and electrophysiological support to the development of novel technologies for recording and manipulating the electrical activity of neurons”.

Funded by EC on “Ionic Neuromodulation For Epilepsy Treatment (IN-FET)”, it is a multidisciplinary collaboration with world-class partners, including IBM Research Zurich, Maastricht University, Sheffield Univ., Udine and Reggio Emilia Universities.

Fields of the research activity: In vitro electrophysiology, patch-clamp and arrays of microelectrodes, cell and tissue culturing, analysis and interpretation of experimental neurobiological data;

Scientist responsible: Michele Giugliano;

Public selection sector: 05/D1 – PHYSIOLOGY S.s.d: BIO/09 - PHYSIOLOGY

Duration of the fellowship: 12 months (renewable)

Gross remuneration per year: € 27170,00

Requisites for the admission to the selection procedure: - University degree: Neuroscience, Biotechnology, Biology, Chemistry, Physics, Bioengineering; - Doctoral degree: Neuroscience, Biophysics, Bioengineering;

Proven experience in: • Research experience in the field of neuroscience and biophysics • Experience in developing different culture systems • Experience in videomicroscopy (DIC) • Experience in electrophysiological studies using patch- clamp and MEA • Knowledge of scientific programming languages (e.g., Matlab, LabView, Phyton) • Proven ability to work in multidisciplinary and biotechnological research projects;

Additional requirements, competencies and abilities: • Ability to generate ideas, conduct experiments autonomy and implement them • Reliability • Interest in understanding the ways in which new micro- and nanoelectronic devices could affect the membrane potential of neuronal cells and, consequently, their electrical activity. • Interest in understanding the processes that govern neuronal excitability at the single cell level and the establishment of specific patterns of neuronal activity within a complex network, both in vitro and in vivo

Duties and responsibilities: • To undertake experiments under the instruction and supervision of the Principal Investigator and in harmony with other lab members • To contribute to the design of experiments in relation to the project • To correctly execute experiments in consultation, ensuring that experiments are appropriately recorded, analyzed and documented both electronically and by maintaining a lab book that will serve as a permanent record of the methodologies used and the experiments performed.

See See

Apply here:

Deadline: 19/04/2022 - 13:00 (CET)

Info: email

Openings: 2020 Two postdoctoral positions in cellular electrophysiology and neurobiology.

Two postdoctoral positions are available immediately at the Neuroscience Area of SISSA - the International School for Advanced Studies, in the lab of Neuronal Dynamics head by Dr. Michele GIUGLIANO.

Both positions are covered for up to 38 months each, on an EC-Horizon 2020 funded project called “Ionic Neuromodulation For Epilepsy Treatment (IN-FET)”. This project combines neurobiology, nanotechnologies, electrochemistry, and electronics together towards a novel breakthrough technology in brain modulation.

At SISSA, we aim at experimentally validating novel routes for cellular and microcircuit stimulation or suppression, in collaboration with a consortium of partners which includes IBM Research Zurich, the University of Geneva, the University of Sheffield, and the Inter-university consortium for Nanoelectronics.

We thus search for experts in in vitro electrophysiology (substrate-integrated microelectrode arrays) and patch-clamp recordings (dissociated cell cultures, acute and organotypic brain tissue slices) with a strong background in quantitative data analysis and an interest for interdisciplinary research.

The deadline for the application is 28/05/2020 and this link to apply.

More information here.

For any scientific information, email to For any administrative information, email to

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